- Dry and irritated nose (inhalation)
- Hypokalaemia (high dose)
Contraiindication: Hypersensitivity to Terbutaline and other sympathomimetic amines.
- Myocardial insufficiency
Interaction: Other Sympathomimetic bronchodilators or epinephrine: Combined effect on the cardiovascular system may be deleterious to the patient. MAOIs and TCAs: Effect of terbutaline on vascular system may be potentiated. Beta-adrenergic blocking agents: Block the pulmonary effect of terbutaline and may produce severe asthmatic attacks in asthmatic patients. Beclomethasone, Theophylline: Synergy when used with these agents. Food: Reduces bioavailability of terbutaline.
Servings: Adult: Oral: Initial dose: 7.5 mg / day in 3 divided doses, if needed dose can be increased to 15mg /day in 3 divided doses. Subcutaneous /Intramuscular/slow IV infusion: 250 - 500mcg 3 - 4 times daily Aerosol inhalation: 250 - 500mcg every 6 - 8 hours Nebulised solution inhalation: 5 - 10 mg every 6 - 12 hours. Children: Oral: Initial dose: 2.5 mg in 2-3 times daily Subcutaneous /Intramuscular/slow IV infusion: 10mcg /kg body weight dose can be increased to 300 mcg / day Aerosol inhalation: 250 - 500mcg every 6 - 8 hours Nebulised solution inhalation: 2 - 5 mg every 6 - 12 hours. Premature labor (IV): Initial dose: 10mcg/minute and dose can be repeated until effective therapeutic response is obtained. Maximum dose: 80mcg/minute. Maintenance dose (IV dosage): Minimum effective dose for 4 hours.