- Transient irritation in the eye
Contraiindication: Hypersensitivity to Sisomicin and other Fluoroquinolones
- Prolonged use
- Stop the use of medicaments if allergic reactions occur
- Avoid contact lenses
- Wear sun glasses if sensitivity to sunlight occurs
Interaction: Aminoglycosides, Amphotericin B, Bacitracin, Cisplatin, Cephalothin, Vancomycin, Methoxyflurane Ethacrynic Acid, Frusemide, Bumetanide & Mannitol: Increased ototoxic, neurotoxic or nephrotoxic affects. Anaesthetics, Neuromuscular blocking agents (Tubocurarine, Gallamine): Risk of neuromuscular blockade and respiratory paralysis. Penicillin, Cephalosporins, Carbenicillin, Ticarcillin: Exert antibiotic synergism, especially useful in pseudomonas infections. Lab tests: Aminoglycoside serum levels: Guard against in-vitro inactivation of aminoglycosides by b-lactum antibiotics in patients on combination therapy.
Servings: The usual dose for adults is 3 mg/kg daily given intramuscularly in 2 or 3 divided doses. It may be given by intravenous infusion if necessary. Adult: 1 - 2 drop to be instilled in to the infected eye every 4-6 hours Trachoma: Treatment is for 1 - 2 months