Jonakayem Pharma Formulation (OPC) Pvt. Ltd.


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Formulary: Generic Formulary
Category: Infections & Infestations
Dosages: 100MG/ 50 mg
Unit of Packing: Inj- 1ml
In treatment of: Treatment of susceptible GM-Ve and Staphylococcal infections

Adverse Effects: 

  • Transient irritation in the eye
  • Ototoxicity

Contraiindication:  Hypersensitivity to Sisomicin and other Fluoroquinolones

Special Precaution: 

  • Prolonged use
  • Stop the use of medicaments if allergic reactions occur 
  • Avoid contact lenses 
  • Wear sun glasses if sensitivity to sunlight occurs

Interaction: Aminoglycosides, Amphotericin B, Bacitracin, Cisplatin, Cephalothin, Vancomycin, Methoxyflurane Ethacrynic Acid, Frusemide, Bumetanide & Mannitol: Increased ototoxic, neurotoxic or nephrotoxic affects. Anaesthetics, Neuromuscular blocking agents (Tubocurarine, Gallamine): Risk of neuromuscular blockade and respiratory paralysis. Penicillin, Cephalosporins, Carbenicillin, Ticarcillin: Exert antibiotic synergism, especially useful in pseudomonas infections. Lab tests: Aminoglycoside serum levels: Guard against in-vitro inactivation of aminoglycosides by b-lactum antibiotics in patients on combination therapy.

Servings: The usual dose for adults is 3 mg/kg daily given intramuscularly in 2 or 3 divided doses. It may be given by intravenous infusion if necessary. Adult: 1 - 2 drop to be instilled in to the infected eye every 4-6 hours Trachoma: Treatment is for 1 - 2 months