Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
SALBUTAMOL + THEOPHYLLINE

SALBUTAMOL + THEOPHYLLINE

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Product: SALBUTAMOL + THEOPHYLLINE
Formulary: Generic Formulary
Category: Respiratory System
Sub Group: ANTIASTHAMATICS
Dosages: 2MG + 100MG; 1 Mg+500mg/5ml
Unit of Packing: Tablets
In treatment of: Releif of acute Bronchospasm

Adverse Effects: 

  • Upset stomach
  • Stomach pain 
  • Diarrhea 
  • Headache
  • Restlessness
  • Insomnia 
  • Irritability
  • Vomiting 
  • Increased or rapid heart rate 
  • Irregular heartbeat 
  • Seizures 
  • Skin rash

Contraiindication: 

  • Hypersensitivity to the drug 
  • Peptic ulcer
  • Underlying seizure disorders

Special Precaution: 

  • Cardiac disease 
  • Hypertension
  • Hyperthyroidism 
  • Hepatic impairment 
  • Fever

Interaction: Benzodiazepines: Sedative effects may be antagonized. Beta agonists: Additive effect. Halothane: Catecholamine induced arrhythmias may occur. Tetracyclines: Theophylline adverse reaction may be enhanced. Food: Theophylline elimination is increased by a low carbohydrate, high protein diet.

Servings: Adults: Long term management of chronic bronchospasm: 300 to 1000 mg daily in divided doses in every 6 to 8 hrs or 175 to 500 mg every 12 hrs for modified release preparations. Bronchospasm- Adults- 5mg/kg body weight every 6 to 8 hrs. Children- 5 mg/kg every 4 to 6 hrs. Neonatal apnoea of prematurity- Child- More than 24days - 5mg/kg as maintenance dose and 1.5mg/kg every 12 hrs as loading dose. Less than 24 days- 1mg/kg every 12 hrs. Intravenous- Management of severe bronchospasm- Adult- 4 to 5 mg/kg as loading dose over 20 to 30 minutes. 0.4 mg/kg/hr as maintenance dose. Children- 4 to 5 mg/kg as loading dose over 20 to 30 minutes. 0.8mg/kg/hr as maintenance dose.