Contraiindication: Coronary insufficiency, first stage of labor, peripheral vascular disease, sepsis, impairment of hepatic and renal function.
Special Precaution: Sepsis, hypertension, obliterative vascular disease.
Interaction: Beta -blockers, methysergide, smoking: Risk of vascular occlusion increased. Erythromycin: Increased plasma concentration of ergotamine. Oral contraceptives: Increased risk of thrombosis.
Servings: Adults: Active management of 3rd stage of labour: Oral: Ergotab: 300-540mg after 3rd stage of labour. Thereafter 150-270mg thrice a day. I.V.: 0.1 to 0.2mg slowly Uterine atony / haemorrhage: 0.2mg I.M. or 0.1 to 0.2mg I.V., may be repeated at intervals of not less than 2 hours. Subinvolution, lochiometra, puerperal bleeding: Oral : 0.125 to 0.25mg Injection: 0.1 to 0.2mg S.C. or I.M., upto 3 times daily. In lactating women preferably not longer than 3 days. Children: Not applicable.