- Abdominal discomfort
- Photosensitivity reactions
- Leg cramps
- Hypersensitivity to Methoxsalen.
- Photosensitivity includes lupus erythematosus,Porphyria cutanea tarda,erythropoietic proto porphyria,Xeroderma pigmentosum.
- Invasive squamous cell carcinoma.
- History of melanoma
- Hepatic impairment
- History of sunlight allergy
- Gastrointestinal diseases
- Avoid contact with eye lids, lips, genitals
- Avoid exposure to sunlight, artificial UV emission
Interaction: Ultraviolet light & overexposure to sunlight: May result in severe burns. Drugs known to cause photosensitation - Griseofulvin, phenothiazines, nalidixic acid, halogenated salicylanilides, tetracyclines, thiazides: Special care should be excercised in treating patients who are taking these drugs.
Servings: Oral: Psoriasis, Vitiligo: 600 mcg/kg to be taken 2-4 hours before exposure to UV light for 2 times a week (minimum 2 days interval between the doses) Topical: 1% Methoxsalen and its diluted solutions are used.