Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
METHOXSALEN

METHOXSALEN

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Product: METHOXSALEN
Formulary: Generic Formulary
Category: Skin
Sub Group: PIGMENTATION DISORDERS
International Brand Name: Oxsoralen
Dosages: 10 GM / 1% W/V
Unit of Packing: Tablets/ Bottles
In treatment of: REPIGMENTATION OF VITILIGINOUS AREAS

Adverse Effects: 

  • Nausea
  • Abdominal discomfort
  • Diarrhoea
  • Headache
  • Dizziness
  • Nervousness
  • Peeling
  • Itching
  • Blistering
  • Erythema
  • Photosensitivity reactions
  • Insomnia
  • Leg cramps
  • Burns

Contraiindication: 

  • Hypersensitivity to Methoxsalen.
  • Photosensitivity includes lupus erythematosus,Porphyria cutanea tarda,erythropoietic proto porphyria,Xeroderma pigmentosum.
  • Aphakia.
  • Invasive squamous cell carcinoma.
  • Albinism.
  • History of melanoma
  • Jaundice

Special Precaution: 

  • Hepatic impairment
  • History of sunlight allergy
  • Gastrointestinal diseases
  • Avoid contact with eye lids, lips, genitals
  • Avoid exposure to sunlight, artificial UV emission

Interaction: Ultraviolet light & overexposure to sunlight: May result in severe burns. Drugs known to cause photosensitation - Griseofulvin, phenothiazines, nalidixic acid, halogenated salicylanilides, tetracyclines, thiazides: Special care should be excercised in treating patients who are taking these drugs.

Servings: Oral: Psoriasis, Vitiligo: 600 mcg/kg to be taken 2-4 hours before exposure to UV light for 2 times a week (minimum 2 days interval between the doses) Topical: 1% Methoxsalen and its diluted solutions are used.