Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
KETOROLAC TROMETAMOL

KETOROLAC TROMETAMOL

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Product: KETOROLAC TROMETAMOL
Formulary: Generic Formulary
Category: Pain & Fever
Sub Group: ANALGESICS & ANTIPYRETICS
International Brand Name: Toradol and Acular
Dosages: 10 MG
Unit of Packing: Tablets
In treatment of: Short term mgt of moderate to severe post opeartive pain

Adverse Effects: 

  • Nausea 
  • Drowsiness 
  • Dizziness 
  • Headache 
  • Syncope 
  • Transient scalp tingling 
  • Orthostatic hypotension 
  • Ventricular arrhythmias 
  • Nasal stuffiness 
  • Broncho spasm 
  • Vomiting 
  • Diarrhea 
  • Muscle spasm 
  • Toxic myopathy 
  • Dry mouth 
  • Ulcer
  • Gastric irritation 
  • Oedema 
  • Dry mouth

Contraiindication: 

  • Hypersensitivity to this drug 
  • Peptic ulcer 
  • As a prophylactic analgesic before surgery; pregnancy and lactation 
  • In elderly patient there is usually hepatic or renal dysfunction 
  • Coagulation disorder

Special Precaution: 

  • Hepatic dysfunction 
  • Renal dysfunction and in to be used with caution 
  • GI disease 
  • Bleeding disorders 
  • Patients with hypersensitivity to other Non Steroidal Anti Inflammatory Drugs

Interaction: Anticoagulants: May prolong prothrombin time. Beta blockers: Antihypertensive effect may be impaired. Cyclosporine: Nephrotoxicity of both agents may be increased. Lithium: Serum lithium levels may be increased resulting in toxicity. Hydantoins: Serum hydantoins levels resulting in increased efficacy and toxic effects. Methotrexate: Risk of methotrexate toxicity (stomatitis, bone marrow suppression, nephrotoxicity) increased. Aspirin: Plasma concentration of ketorolac may be decreased and may increase the incidence of GI effects.

Servings: For Injection- Adults-Initially 60mg i.m. or 30mg i.v. as a single dose, or 30 mg i.m or i.v. every 6 hrs. In the case of renal impaired patient, initially 30mg i.m .or 15mg i.v. as a single doses or multiple doses of 15mg i.m. or i.v.every 6 hrs. For oral- Adults- 20mg as a single dose followed by 10mg every 4 to 6 hrs. In the case of renal impaired patients 10mg as a single dose, followed by 10mg every 4 to 6 hrs.