Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
KETOCONAZOLE

KETOCONAZOLE

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Product: KETOCONAZOLE
Formulary: Generic Formulary
Category: Infections & Infestations
Sub Group: ANTIFUNGALS
International Brand Name: Perkhotal, Nizoral
Dosages: 200MG
Unit of Packing: Tablets
In treatment of: Blastomycosis;chronic mucocutaneous candidiasis;Coccidioidomycosis;Histoplasmosis;Oral thrush;Paracoccidioidomycosis;Candidiasis;Chromomycosis;Candiduria

Adverse Effects: 

  • Dizziness
  • Headach
  • Nausea
  • Vomiting
  • Diarrhoea
  • Anorexia
  • Gynecomastia
  • Loss of hair
  • Libido
  • Leucopenia
  • Pruritis
  • Psychiatric problems

Contraiindication: Hypersensitivity to Ketoconazole

Special Precaution: Hepatic dysfunction

Interaction: Antacids & Histamine H2 antagonists: Increased gastric pH may inhibit ketoconazole absorption. Isoniazid: The bioavailability of Ketoconazole may be decreased. Rifampicin: Decreased serum levels of either drug may occur. Oral anticoagulants: Anticoagulants response may be enhanced. Corticosteroids: Bioavailability of corticosteroids increased and clearance may be decreased, resulting in possible toxicity. Cyclosporine: Efficacy of cyclosporine enhanced leading to nephrotoxicity. May be used beneficially to reduce dose of cyclosporine in some patients. Theophelline: Serum levels of theophylline may be decreased. Alcohol: Nausea and acute facial flushing.

Servings: Adult: 200 - 400 mg once daily Prostate carcinoma: 1.2 g in 3 divided dose. TOPICAL PREPARATIONS For the treatment of Tinea infections apply once or twice daily on the affected part for 14 days. Seborrheic dermatitis: apply Ketoconazole twice daily for 1 month Dandruff: Apply for 60 seconds and rinse well. Reapply for 180 seconds. Apply twice weekly for 1 month CHILDREN>2 years: 3.3 - 6.6 mg / kg body weight / day TOPICAL PREPARATIONS For the treatment of Tinea infections apply once or twice daily on the affected part for 14 days. For Tinea pedis, apply for 1