Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
KETOCONAZOLE

KETOCONAZOLE

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KETOCONAZOLE 

Sub Group Generic Formulary Brand Name Dosages Unit In treatment of Adverse Effects Contraiindication Special Precaution Interaction Servings

KETOCONAZOLE Perkhotal, Nizoral 2 % W/W Tube/ Bottles Treatment of Pityriasis Versicolor 1.Dizziness
2.Headach
3.Nausea
4.Vomiting
5.Diarrhoea
6.Anorexia
7.Gynecomastia
8.Loss of hair
9.Libido
10.Leucopenia
11.Pruritis
12.Psychiatric problems
1.Hypersensitivity to Ketoconazole Hepatic dysfunction Antacids & Histamine H2 antagonists: Increased gastric pH may inhibit ketoconazole absorption.
Isoniazid: The bioavailability of Ketoconazole may be decreased.
Rifampicin: Decreased serum levels of either drug may occur.
Oral anticoagulants: Anticoagulants response may be enhanced.
Corticosteroids: Bioavailability of corticosteroids increased and clearance may be decreased, resulting in possible toxicity.
Cyclosporine: Efficacy of cyclosporine enhanced leading to nephrotoxicity. May be used beneficially to reduce dose of cyclosporine in some patients.
Theophelline: Serum levels of theophylline may be decreased.
Alcoahol: Nausea and acute facial flushing.
Adult: 200 - 400 mg once daily
Prostate carcinoma: 1.2 g in 3 divided dose.
TOPICAL PREPARATIONS
For the treatment of Tinea infections apply once or twice daily on the affected part for 14 days.
Seborrheic dermatitis: apply Ketoconazole twice daily for 1 month
Dandruff: Apply for 60 seconds and rinse well. Reapply for 180 seconds. Apply twice weekly for 1 month
CHILDREN>2 years: 3.3 - 6.6 mg / kg body weight / day
TOPICAL PREPARATIONS
For the treatment of Tinea infections apply once or twice daily on the affected part for 14 days.
For Tinea pedis, apply for 1 ½ month.
Seborrheic dermatitis: apply Ketoconazole twice daily for 1 month