Jonakayem Pharma Formulation (OPC) Pvt. Ltd.


Send Inquiry
Formulary: Generic Formulary
Category: Diabetes
Dosages: 1 MG/2mg/3mg
Unit of Packing: Tablets
In treatment of: treatment of type Diabetes Mellitus

Adverse Effects: 

  • Hypoglycemia
  • Nausea 
  • Vomiting
  • Diarrhoea 
  • Constipation 
  • Headache 
  • Paresthesia 
  • Hypersensitivity reactions 
  • Rashes 
  • Photosensitivity 
  • Purpura
  • Transient leucopenia 
  • Agranulocytosis
  • Temporary visual impairment


  • Hypersensitivity to the drug
  • Diabetic ketoacidosis 
  • Diabetic coma 
  • Juvenile diabetes mellitus

Special Precaution: 

  • Malnourished and deliberate individuals 
  • Strenous exercise and irregular meals may leads to hypoglycemia 
  • Hepatic impairment 
  • Renal impairment 
  • Monitor glucose levels during therapy 
  • Adrenal insufficiency 
  • Pituitary insufficiency 
  • Any work requiring mental alertness such as operating a vehicle or machine

Interaction: Hypoglycaemic effect of glimepiride is enhanced by : Anticoagulants, Androgens, Chloramphenicol, Clofibrate, Fenfluramine, Fluconazole, Gemfibrozil, Histamine H2 anta-gonists, Magnesium Salts, Methyldopa, MAOIs, Phenylbutazone, Probenecid, Salicylates, Sulfinpyrazone, Sulfonamides, TCAs, & Urinary acidifiers. Hypoglycemic effect of glimepiride inhibited by the following drugs : Beta-blockers, Cholestyramine, Diazoxide, Hydantoins, Rifampicin, Thiazide diuretics & Urinary alkalisers. Charcoal : Reduces the absorption of glimepiride thus reducing its efficacy or toxicity. Digitalis glycosides : Coadministration results in increased digitalis serum levels

Servings: Oral: Starts with 1mg daily; immediately before 1st main meals. Adjust the dosage by increments of 1to 2mg at 1 to 2week intervals based on patients response up to 6mg/day as required. Maintenance dosage: 1 to 4mg once daily Maximum dose: 8mg once daily