Jonakayem Pharma Formulation (OPC) Pvt. Ltd.


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Sub Group Generic Formulations Brand name Dosages Unit In treatment of Adverse Effects Contraiindication Special Precaution Interaction Servings

.03%w/V 5ML E/E SOLN Treatment of superficial infections of Eye 1. Vestibular damage & Ototoxicity
2. Allergic manifestations
3. Nephrotoxicity
4. Dizziness
5. Nausea
6. Vomiting
7. Seizures
1. Hypersensitive to the drug or other amino glycosides
2. Along with chloaramphenicol or tetracycline
3. Renal impairment
4. Labyrinthine disorders

1. Renal impairment
2. Neuromuscular disorders
Amphotericin B, Cisplatin, Cephalosporin, Vancomycin, Methoxyflurane, Frusemide, Bumetanide: Increased nephrotoxicity.
Anaesthetics, Neuromuscular blocking agents (Tubocurarine): Risk of neuromuscular blockade and respiratory paralysis.
Penicillin, Cephalosporins, Carbenicillin, Ticarcillin: Exert antibiotic synergism, especially useful in Pseudomonas infections.
Loop diuretics: Concurrent use of these agents may increase the risk of respiratory paralysis and renal dysfunction.
Lab Tests: Aminoglycoside serum levels: Guard against in vitro inactivation of aminoglycosides by b-lactum antibiotics in patients on combination therapy.
Adults: 2 to 5mg/kg/day; Thrice daily for a week or more
Children: 2 to 2.5mg/kg; Thrice daily.