Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
ETOPOSIDE

ETOPOSIDE

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Sub Group Generic Formulary Brand Name Dosages Unit In treatment of Adverse Effects Contraiindication Special Precaution Interaction Servings

ETOPOSIDE Etopophos,Toposar, VePesid 50 mg/ 100 mg Capsule/ Vial Treatment of Testicular Tumour,Lung Cancer,Tumours of the Brain,Git,Ovary and Thymus,acute Lymphomas 1. Nausea
2. Vomiting
3. Difficulty in breathing
4. Closing of the throat
5. Bone marrow suppression
6. Bruising or unusual bleeding
7. Tarry stools
8. Fever
9. Chills
10. Congestive heart failure
11. Diarrhea
12. Loss of appetite
13. Facial flushing
14. Darkening of skin and nails
15. Alopecia
16. Red urine
17. Leukemia
18. Hyperpyrexia
19. Amenorrhea
20. Anaphylaxis
21. Photosensitivity
22. Premature menopause
23. Thrombocytopenia
24. Neutropenia
25. Leucopenia
26. Conjunctivitis
27. Keratitis
28. Swelling of the lips, tongue and face
29. Peripheral neuropathy
30. Hypotension
31. Jaundice
32. Bronchospasm
1. Hypersensitivity to the drug
2. Severe bone marrow depression
3. Hepatic dysfunction
1. Renal dysfunction
2. Treatment with cytotoxic drug
3. Recent radiation
4. Extravasations
5. Infection
6. Contraception
7. Monitor patient`s hepatic, renal and haematological functions regularly.
Warfarin: Prolongation of prothrombin time may occur.
Other cytotoxic drugs: Synergism.
Adult-
For small cell carcinoma of the lung-
70mg/metre square/day orally for 4 days OR 100mg/metre square /day orally for 5 days
Repeat the treatment every 3-4 weeks
For testicular carcinoma-
50-100mg/metre square intravenously daily for 5 days OR 100mg/metre square/day on days 1, 3, and 5 days
Repeated the treatment every 4 weeks
For Kaposi`s sarcoma-
150mg/metre square for 3 consecutive days every 4 weeks
Repeat the dose as necessary