Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
EPIRUBICIN

EPIRUBICIN

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Sub Group Generic Formulary Brand Name Dosages Unit In treatment of Adverse Effects Contraiindication Special Precaution Interaction Servings

EPIRUBICIN Ellence,Pharmorubicin , Epirubicin Ebewe 10 mg/ 50 mg Vial Treatment of Breast Cancer & adjuvant treatment of early Breast Cancer w//+ve Lymph nodes 1. Nausea
2. Vomiting
3. Difficulty in breathing
4. Closing of the throat
5. Bone marrow suppression
6. Bruising or unusual bleeding
7. Tarry stools
8. Fever
9. Chills
10. Congestive heart failure
11. Diarrhea
12. Loss of appetite
13. Facial flushing
14. Darkening of skin and nails
15. Alopecia
16. Red urine
17. Leukemia
18. Hyperpyrexia
19. Amenorrhea
20. Anaphylaxis
21. Photosensitivity
22. Premature menopause
23. Thrombocytopenia
24. Neutropenia
25. Leucopenia
26. Conjuctivitis
27. Keratitis
28. Swelling of the lips, tongue and face
1. Hypersensitivity to the drug
2. Hypersensitivity to other anthracycline and anthracenediones
3. Hepatic impairment
4. Myocardial insufficiency
5. Myocardial infarction
6. Severe arrhythmia
7. Cardiac disease
8. Previous therapy with anti tumor drugs in high doses
1. Previous extensive radiotherapy
2. Bone infiltration by tumor
3. Recent immunizations

Intravenous-
Adults-
135 mg/metre square as a single agent and 120mg/metre square in combination every 3 to 4 weeks for the treatment of breast cancer
100mg/metre square every 3 to 4 weeks for the treatment of early breast cancer