Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
DOXAPRAM

DOXAPRAM

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  • Product: DOXAPRAM
  • Formulary: Generic Formulary
  • Category: Respiratory System
  • Sub Group: RESPIRATORY STIMULANTS
  • International Brand Name: Dopram
  • Dosages: 200 MG
  • Unit of Packing: Inj-5ml
  • In treatment of: Post opeartive Respiratory Depression
Adverse Effects: 
  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Seizure
  • Chest pain
  • Heart rate variation
  • Hypertension
  • Laryngospasm
  • Sneezing
  • Urine retention
  • Bronchospasm
  • Hiccups
  • Pruritis
  • Hyperactivity
Contraiindication: 
  • Hypersensitivity to Doxapram
  • Heart failure
  • Hypertension
  • Seizure
  • Head injury
  • Dyspnea
  • Pulmonary embolism
  • Pneumothorax
  • Obstructed air way
  • Acute bronchial asthma
  • Muscle paresis
  • Flail chest
  • Head injury
Special Precaution: 
  • Hepatic impairment
  • Heart diseases
  • Obstructive air way disease
Interaction: 
Sympathomimetics or MAOIs: Additive pressor effects. Halothane, Cyclopropane & Enflurane: Delay initiation of therapy for at least 10 minutes following discontinuation of anaesthetics. Muscle Relaxants: May mask residual effects of muscle relaxants. Theophylline: Agitation, muscle fasciculation and hyperactivity. Morphine: Antagonises morphine induced respiratory depression. Alkaline solutions like Aminophylline, Frusemide & Thiopentone: Precipitation occurs.

Servings: 

Post anaesthesia respiratory stimulation as IV: 0.5 - 1 mg / kg body weight if necessary repeat after 1 hour Drug induced CNS depression: Initial dose IV injection: 2 mg / kg body weight if necessary repeat after 5 minutes and again 1 - 2 hour until patient awakens. Maximum daily dose: 3 g Acute respiratory failure IV infusion: 1.5 - 4 mg / minute