Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
CARBOPLATIN

CARBOPLATIN

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Sub Group Generic Formulary Brand Name Dosages Unit In treatment of Adverse Effects Contraiindication Special Precaution Interaction Servings

CARBOPLATIN Paraplatin 150 MG/450 mg Inj-15ml ADVANCED OVARIAN CARCINOMA 1. Nausea
2. Vomiting
3. Lowered resistance to infection
4. Bruising or unusual bleeding
5. Anemia
6. Weakness
7. sore in mouth
8. Taste changes
9. Diarrhea
10. Loss of appetite
11. Visual changes
12. Black, tarry stools
13. Blood in urine or in stool
14. Cough or hoarseness
15. Fever
16. Chills
17. Myelosuppression
18. Mucositis
19. Dermatitis
20. Angina
21. Heart attack
22. Alopecia
23. Conjunctivitis
24. Cardiac arrhythmias
25. Hyper pigmentation
26. Breathlessness
27. Euphoaria
28. Ataxia
29. Nystagmus
30. Leucopenia
31. Thrombocytopenia
32. Anaphylaxis
33. Agranulocytosis
34. Myocardial ischemia
35. Raised alkaline phosphatase level
36. Serum electrolyte level abnormalities
37. Pain
38. Asthenia
39. Central neurotoxicity
40. Peripheral neuropathies
41. Ototoxicity
42. Blood urea level elevations
43. Embolism
44. Cerebrovascular accidents
45. Mucositis
1. Hypersensitivity to the drug, platinum containing compounds and mannitol
2. Severe bone marrow depression
3. Bleeding
1. Diminished renal function
2. Amino glycosides neurotoxicity
3. Liver function impairment
Phenytoin : Serum concentration may be decreased resulting in loss of therapeutic effect. Intravenous
Adult-
300-600mg/metre square i.v.infusion every 3-4 weeks
For brain tumors in children-
175mg/metre square weekly for 4 weeks, with a 2 weeks recovery period between courses