Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
BUPROPION HYDROCHLORIDE

BUPROPION HYDROCHLORIDE

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Sub Group Generic Formulary Brand Name Dosages Unit In treatment of Adverse Effects Contraiindication Special Precaution Interaction Servings
ANTI-SMOKING BUPROPION HYDROCHLORIDE Zyban 150 MG Tablets- Sustained Release SMOKING CESSATION 1. Nausea
2. Dry mouth
3. Insomnia
4. Agitation
5. Headache
6. Sedation
7. Anxiety
8. Tremor
9. Dizziness
10. Confusion
11. Hearing disturbances
12. Arrhythmia
13. Tachycardia
14. Vomiting
15, Anorexia
16. Excessive sweating
17. Priapism
18. Rash
1. Hypersensitivity to Bupropion
2. Seizure disorder
3. Patient on MAOI (Monoamine oxidase inhibitor) therapy
4. Bulimia nervosa
1. Liver disease
2. Severe kidney disease
3. Hypertension
4. Myocardial infarction
5. History of seizure disorder
6. Alcoholics
7. Patient on MAOI therapy (Discontinue the MAO inhibitor at least 2 weeks before Bupropion is started)
8. Use caution while driving vehicle, operating machine and activities requiring mental alertness or judgment

Adult
Depression:
Initial dose: 150 - 200 mg / day in 2divided doses. If sufficient response do not occur after 3 days dose can be increased to 300 mg / day in 3 divided doses.
Maximum dose: 450 mg / day
Smoking cessation treatment: Initial dose: 150 mg daily for 3 days then dose is increased to 300 mg / day in 2 divided doses for 7 - 12 weeks