Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
BROMOCRIPTINE

BROMOCRIPTINE

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Product: BROMOCRIPTINE
Formulary: Generic Formulary
Category: Fertility & Antifertility Agents
Sub Group: OVULATION INDUCERS
International Brand Name: Hypogonadism Galactrorrhea;Infertility
Dosages: Parlodel
Unit of Packing: 1.25 MG/2.5 mg
In treatment of: Tablets

Adverse Effects: 

  • Hypotension
  • Nausea
  • Vomiting
  • Constipation
  • Headache
  • Dizziness
  • Skin rash
  • Dry mouth

Contraiindication: 

  • Hypersensitivity to Bromocriptine and other ergot derivatives
  • Preeclampsia

Special Precaution: 

  • Renal impairment
  • Hepatic impairment
  • Myocardial infarction
  • Arrhythmia
  • History of psychosis
  • Peptic ulcer
  • Diabetes mellitus
  • Concurrent antihypertensive therapy.
  • Use caution when driving vehicle operating machine or activities requiring mental alertness

Interaction: Antihypertensives: Efficacy potentiated by concomitant use of bromocriptine dopamine antagonists. Phenothiazines, butyrophenones: Decreases efficacy of these drugs. Erythromycin: increases efficacy of bromocriptine. Alcohol: Decreases tolerance to bromocriptine and vice-versa.

Servings: Adult: Parkinson`s disease: Initial dose: 1 - 1.25 mg at night with food for 1 week. 2 - 2.5 mg at night with food for 2nd week 5 mg / day in 2 divided doses for 3rd week 7.5 mg / day in 3 divided doses for 4th week.Then increase the dose by 2.5 mg daily every 3 - 14 days until sufficient therapeutic response is obtained Maintenance dose: 10 - 40 mg/day.Maximum dose: 100 mg / day Amenorrhea and Galactorrhea associated with hyperprolactinemia: Initial dose: 1.25 - 2.5 mg / day increase the dose by 2.5 mg daily every 3 - 7 days until sufficient therapeutic response is obtained. Maintenance dose: 5 - 7.5 mg/day.Maximum dose: 40 mg / day Acromegaly: Initial dose: 1.25 - 2.5 mg at night for 3 days increase the dose by 1.25 - 2.5 mg daily every 3 - 7 days until sufficient therapeutic response is obtained.Dose range: 20 - 30 mg / day in divided doses. Maximum dose: 100 mg / day Hepatic encephalopathy: Initial dose: 1.25 mg / day increase the dose by 1.25 mg every 3 days until sufficient therapeutic response (15 mg) is obtained. Premenstrual syndrome 5 -15 mg in 2 divided doses 10th day of menstrual cycle until onset of menstruation Cushing`s syndrome: 1.25 - 2.5 mg 2 - 4 times daily Suppression of established lactation: 2.5mg daily for 2 to 3 days. Subsequently increased to 2.5mg twice daily for two weeks. Children: Not recommended