Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
ATROPINE

ATROPINE

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Sub Group Generic Formulary Brand Name Dosages Unit In treatment of Adverse Effects Contraiindication Special Precaution Interaction Servings

ATROPINE
0.GMG/ML Bottle- 10ml Organophosphorus Poisioning 1. Dry mouth
2.Constipation
3.Difficulty in swallowing
4.Tachycardia
5.Headache
6.Restlessness
7.Insomnia
8.Dizziness
9.Nausea
10.Vomiting
11.Decreased secretions
12.Irritation at the site of injection site
13.Fever
14.Retention of urine




1.Hypersensitivity to Atropine and other belladonna alkaloids
2.Tachycardia
3.Obstructive disease of gastrointestinal tract
4.Obstructive uropathy
5.Unstable cardiovascular status in acute haemorrhage

7.Paralytic ileus
8.Toxic megacolon
9.Intestinal atony
10.Asthma
11.Myasthenia gravis
12.Thyrotoxicosis
1.Any work that require mental alertness like drivingoperating machineAlcoholics
Parenteral
Adult:
Pre anaesthetic medication: (IM) or (SC) 300-600mcg is given 30-60 minutes before surgery.
Bradycardia (IV ): 0.3 - 1 mg dose can be repeated every 3 - 5 minutes 0.03 mg / kg in patient with mild Bradycardia and 0.4 mg / kg with severe Bradycardia,
To block the adverse muscarinic effect of anticholinesterase agents: 0.6 - 1.2 mg for each 0.5 - 2.5 mg of Neostigmine administered intravenously a few minutes before anticholinesterase agents.
Antidote for anticholinesterase insecticidal poisoning: (IM or IV): Initial dose: 1 - 2mg is given and dose can be increased up to 6 mg in severe cases and repeat the dose every 5 - 60 minutes until muscarinic symptoms disappears.
Prevention of Bronchospasm: 0.025 mg / kg is administered with the help of a nebulisers 3 - 4 times daily up to 2.5 mg
Children
Premedication: (IM) or (SC): 20mcg/kg.
Bradycardia (IV): 10 - 20 mcg/kg doses can be repeated up to 1 mg
Antidote for anticholinesterase insecticidal poisoning: (IM or IV): Initial dose: 0.05 mg / kg is given and repeat the dose every 10 -30 minutes until muscarinic symptoms disappears