Jonakayem Pharma Formulation (OPC) Pvt. Ltd.
ACICLOVIR

ACICLOVIR

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Product: ACICLOVIR
Formulary: Generic Formulary
Category: Skin
Sub Group: MISCELLANEOUS SKIN PREPARATION
International Brand Name: Cyclovir, Herpex, Acivir,Acivirax, Zovirax and Zovir
Dosages: 5 % W/W
Unit of Packing: Tube- 5 gm
In treatment of: HERPES SIMPLEX INFECTIONS OF THE SKIN

Contraiindication: Hypersensitivity to Acyclovir

Special Precaution: 

  • Renal impairment
  • Psychiatric problems
  • Depression
  • Patients taking nephrotoxic drugs
Adverse Effects: 
  • Nausea
  • Vomiting
  • Burning
  • Stinging
  • Tremor
  • Hallucinations
  • Lethargy
  • Phlebitis
  • Malaise
Interaction: Probenecid: Increases efficacy by decreasing urinary excretion and increasing half-life. Zidovudine: Causes severe drowsiness and lethargy.

Servings: Adult: Herpes zoster infection: 1 - 4 g / day in 5 divided doses (take every 4 hour while awake) for 7 - 10 days dose is depend upon the severity, duration and type of infection HSV in immunocompromised patient: 1 - 4 g / day in 5 divided doses (take every 4 hour while awake): dose is depend upon the severity, duration and type of infection Genital herpes: 1g / day in 5 divided dose (take every 4 hour while awake) for 10 days Genital herpes in immunocompromised patient: 1 - 2 g / day in 3 - 5 divided dose Chicken pox: 3. 2g / day in 4 divided dose for 5 days Herpes zoster ophthalmicus: 3 g / day in 5 divided dose (take every 4 hour while awake) for 10 days Children: Herpes zoster / Herpes simplex: 15 mg / kg body weight / day in 3 divided dose Chicken pox: 80 mg / kg body weight / day in 4 divided dose for 5 days